Synaptic Transmission:  Figures and animation

These images illustrate the general process of synaptic transmission.  The six steps in synaptic transmission are illustrated and described below.  Review these figures then take a look at the synaptic transmission animation (48 k).  

Synaptic transmission frame 1 Step 1. The neurotransmitter is manufactured by the neuron and stored in vesicles at the axon terminal.
Synaptic transmission frame 2 Step 2. When the action potential reaches the axon terminal, it causes the vesicles to release the neurotransmitter molecules into the synaptic cleft.
Synaptic transmission frame 3 Step 3. The neurotransmitter diffuses across the cleft and binds to receptors on the post-synaptic cell.

Step 4. The activated receptors cause changes in the activity of the post-synaptic neuron.

Synaptic transmission frame 4 Step 5. The neurotransmitter molecules are released from the receptors and diffuse back into the synaptic cleft.
Synaptic transmission frame 5
Synaptic transmission frame 6 Step 6. The Neurotransmitter is re-absorbed by the post synaptic neuron. This process is known as Reuptake.

 

 

   
      copyright (c) 2008 Michael R. Markham Updated: April 25, 2008